Bruises and sprains may be treated with an oral dose of neem leaf tea supplemented by either a wrap soaked in warmed neem cream or a paste of crushed neem leaves. Neem as a topical preparation helps increase blood flow to the bruised area. This helps remove the discoloration and promote healing. Oral doses of neem leaf provide compounds that reduce inflammation, widen blood vessels and reduce pain. In test with neem extract, aspirin and Indomethacin neem extracts provided up to 50% more inhibition of inflammation than either of the standard drugs. Neem oil and leaf extracts applied topically provides anti-inflammatory and pain relieving properties that are absorbed into the local area.